Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum: A case-based review

Julio Alejandro Cerna-López; Paul J. Tejada-Llacsa; Fiorella Andrea de Jesús Valle-Farfán; Graciela S. Alarcón; Manuel F. Ugarte-Gil; Víctor R. Pimentel-Quiroz

doi:10.1016/j.rcreu.2021.06.001

Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum: A case-based review

Translated title of the contribution: Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum: A case-based review

Julio Alejandro Cerna-López, Paul J. Tejada-Llacsa, Fiorella Andrea de Jesús Valle-Farfán, Graciela S. Alarcón, Manuel F. Ugarte-Gil, Víctor R. Pimentel-Quiroz

Medicina humana

Research output: Contribution to journal › Article › peer-review

Abstract

Clinically amyopathic dermatomyositis (CADM) is associated with antibodies directed against the protein encoded by the melanoma differentiation-associated gene 5 (MDA5). CADM patients have an increased risk of developing rapidly progressive interstitial lung disease (RP-ILD) and spontaneous pneumomediastinum. Two Peruvian cases of RP-ILD-associated CADM with spontaneous pneumomediastinum are presented, one of them was anti-MDA5 antibody positive. To our knowledge, this is the first report of anti-MDA5-associated CADM in the Peruvian population.

Translated title of the contribution	Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum: A case-based review
Original language	English
Pages (from-to)	277-282
Number of pages	6
Journal	Revista Colombiana de Reumatologia
Volume	30
Issue number	3
DOIs	https://doi.org/10.1016/j.rcreu.2021.06.001
State	Published - 1 Jul 2023

Keywords

Anti-MDA5 antibodies
Clinically amyopathic dermatomyositis
Spontaneous pneumomediastinum

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10.1016/j.rcreu.2021.06.001

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Cerna-López, J. A., Tejada-Llacsa, P. J., Valle-Farfán, F. A. D. J., Alarcón, G. S., Ugarte-Gil, M. F., & Pimentel-Quiroz, V. R. (2023). Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum: A case-based review. Revista Colombiana de Reumatologia, 30(3), 277-282. https://doi.org/10.1016/j.rcreu.2021.06.001

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title = "Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum: A case-based review",

abstract = "Clinically amyopathic dermatomyositis (CADM) is associated with antibodies directed against the protein encoded by the melanoma differentiation-associated gene 5 (MDA5). CADM patients have an increased risk of developing rapidly progressive interstitial lung disease (RP-ILD) and spontaneous pneumomediastinum. Two Peruvian cases of RP-ILD-associated CADM with spontaneous pneumomediastinum are presented, one of them was anti-MDA5 antibody positive. To our knowledge, this is the first report of anti-MDA5-associated CADM in the Peruvian population.",

keywords = "Anti-MDA5 antibodies, Clinically amyopathic dermatomyositis, Spontaneous pneumomediastinum",

author = "Cerna-L{\'o}pez, {Julio Alejandro} and Tejada-Llacsa, {Paul J.} and Valle-Farf{\'a}n, {Fiorella Andrea de Jes{\'u}s} and Alarc{\'o}n, {Graciela S.} and Ugarte-Gil, {Manuel F.} and Pimentel-Quiroz, {V{\'i}ctor R.}",

note = "Publisher Copyright: {\textcopyright} 2021 Asociaci{\'o}n Colombiana de Reumatolog{\'i}a",

year = "2023",

month = jul,

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doi = "10.1016/j.rcreu.2021.06.001",

language = "Ingl{\'e}s",

volume = "30",

pages = "277--282",

journal = "Revista Colombiana de Reumatologia",

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Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum: A case-based review. / Cerna-López, Julio Alejandro; Tejada-Llacsa, Paul J.; Valle-Farfán, Fiorella Andrea de Jesús et al.
In: Revista Colombiana de Reumatologia, Vol. 30, No. 3, 01.07.2023, p. 277-282.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum

T2 - A case-based review

AU - Cerna-López, Julio Alejandro

AU - Tejada-Llacsa, Paul J.

AU - Valle-Farfán, Fiorella Andrea de Jesús

AU - Alarcón, Graciela S.

AU - Ugarte-Gil, Manuel F.

AU - Pimentel-Quiroz, Víctor R.

PY - 2023/7/1

Y1 - 2023/7/1

N2 - Clinically amyopathic dermatomyositis (CADM) is associated with antibodies directed against the protein encoded by the melanoma differentiation-associated gene 5 (MDA5). CADM patients have an increased risk of developing rapidly progressive interstitial lung disease (RP-ILD) and spontaneous pneumomediastinum. Two Peruvian cases of RP-ILD-associated CADM with spontaneous pneumomediastinum are presented, one of them was anti-MDA5 antibody positive. To our knowledge, this is the first report of anti-MDA5-associated CADM in the Peruvian population.

AB - Clinically amyopathic dermatomyositis (CADM) is associated with antibodies directed against the protein encoded by the melanoma differentiation-associated gene 5 (MDA5). CADM patients have an increased risk of developing rapidly progressive interstitial lung disease (RP-ILD) and spontaneous pneumomediastinum. Two Peruvian cases of RP-ILD-associated CADM with spontaneous pneumomediastinum are presented, one of them was anti-MDA5 antibody positive. To our knowledge, this is the first report of anti-MDA5-associated CADM in the Peruvian population.

KW - Anti-MDA5 antibodies

KW - Clinically amyopathic dermatomyositis

KW - Spontaneous pneumomediastinum

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U2 - 10.1016/j.rcreu.2021.06.001

DO - 10.1016/j.rcreu.2021.06.001

M3 - Artículo

AN - SCOPUS:85111033501

SN - 0121-8123

VL - 30

SP - 277

EP - 282

JO - Revista Colombiana de Reumatologia

JF - Revista Colombiana de Reumatologia

IS - 3

ER -

Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum: A case-based review

Abstract

Keywords

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