Abstract
Integrons from a clinical strain of Acinetobacter baumannii highly resistant to β-lactams have been analyzed. The largest (2.2 kb) contained three gene cassettes: an aacA4, an open reading frame of 417 nucleotides, and an OXA-type encoding gene. The oxa gene nucleotide sequence differed from that of the oxa-20 in 2 bp, one of the mutations being silent. The nonsilent mutation generated a substitution of glutamic acid for aspartic acid. The new OXA has been named OXA-37.
Original language | English |
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Pages (from-to) | 261-265 |
Number of pages | 5 |
Journal | Microbial Drug Resistance |
Volume | 8 |
Issue number | 4 |
DOIs | |
State | Published - 2002 |