Carrion's disease: An eradicable illness?

Cláudia Gomes, Maria J. Pons, Juana del Valle Mendoza, Joaquim Ruiz

Research output: Contribution to journalComment/debate

17 Scopus citations

Abstract

Carrion's disease is a neglected tropical disease caused by Bartonella bacilliformis, a vector-borne pathogen restricted to the Andean valleys of Peru, Ecuador and Colombia. Carrion's disease is a biphasic illness; in the acute phase the case-fatality rate can be as high as 88 %, related to high parasitemia, arriving to almost all erythrocytes, and secondary bacterial infections close related with the development of transient immunosuppression in the earlier illness phases. In addition, there are an undefined number of asymptomatic carriers that are reservoirs of the etiological agent of Carrion's disease in endemic areas, they make take into account due to they are the perpetuators of this disease. The actual scenario of Carrion's disease, in which the illness is arriving to new areas, due to the expansion of the vector's distribution, suggests that now may be a crucial time to design a strategy focusing on its elimination.

Original languageEnglish
Article number105
JournalInfectious Diseases of Poverty
Volume5
Issue number1
DOIs
StatePublished - 1 Dec 2016

Keywords

  • Bartonella bacilliformis
  • Carrion's disease
  • Colombia
  • Ecuador
  • Eradication
  • Neglected tropical diseases
  • Oroya fever
  • Peru
  • South America

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