TY - JOUR
T1 - Cardiovascular disease in human immunodeficiency virus-infection as a cause of hospitalization
T2 - A case-series in a General Hospital in Peru
AU - Valenzuela-Rodríguez, Germán
AU - Mezones-Holguín, Edward
AU - Mendo-Urbina, Fernando
AU - Rodríguez-Morales, Alfonso J.
N1 - Publisher Copyright:
© 2015 Elsevier Editora Ltda.
PY - 2015/7/1
Y1 - 2015/7/1
N2 - Cardiovascular disease in the context of human immunodeficiency virus infection has become a major clinical concern in recent years. In the current report we assess hospitalizations due to cardiovascular disease in human immunodeficiency virus patients in a Social Security reference hospital in Peru. Methods: A retrospective study was carried out between January 1996 and December 2012 in a General Hospital in Lima, Peru. Results: We included 26 patients hospitalized due to cardiovascular disease. Mean age was 46.3 years (SD 12.5), predominantly male (57.7%). Ten patients (38.4%) were in Acquired Immunodeficiency Syndrome stages. Seventeen (65.4%) received high-active-antiretroviral therapy. Eleven (42.3%) had cardiac involvement and 15 (57.7%) had non-cardiac vascular involvement. The most frequent causes of cardiac involvement were pericardial effusion and myocardial infarction. On the other hand, deep vein thrombosis and stroke were the most frequent for non-cardiac vascular involvement. Conclusions: Cardiovascular disease is an important cause of hospitalization in Peruvian human immunodeficiency virus patients, with differences between immunosuppression stages. Further studies analyzing associated factors are warranted.
AB - Cardiovascular disease in the context of human immunodeficiency virus infection has become a major clinical concern in recent years. In the current report we assess hospitalizations due to cardiovascular disease in human immunodeficiency virus patients in a Social Security reference hospital in Peru. Methods: A retrospective study was carried out between January 1996 and December 2012 in a General Hospital in Lima, Peru. Results: We included 26 patients hospitalized due to cardiovascular disease. Mean age was 46.3 years (SD 12.5), predominantly male (57.7%). Ten patients (38.4%) were in Acquired Immunodeficiency Syndrome stages. Seventeen (65.4%) received high-active-antiretroviral therapy. Eleven (42.3%) had cardiac involvement and 15 (57.7%) had non-cardiac vascular involvement. The most frequent causes of cardiac involvement were pericardial effusion and myocardial infarction. On the other hand, deep vein thrombosis and stroke were the most frequent for non-cardiac vascular involvement. Conclusions: Cardiovascular disease is an important cause of hospitalization in Peruvian human immunodeficiency virus patients, with differences between immunosuppression stages. Further studies analyzing associated factors are warranted.
KW - Acquired Immunodeficiency Syndrome
KW - Cardiovascular diseases
KW - HIV
KW - Peru
UR - http://www.scopus.com/inward/record.url?scp=84938208430&partnerID=8YFLogxK
U2 - 10.1016/j.bjid.2015.03.001
DO - 10.1016/j.bjid.2015.03.001
M3 - Artículo
C2 - 25892316
AN - SCOPUS:84938208430
SN - 1413-8670
VL - 19
SP - 431
EP - 435
JO - Brazilian Journal of Infectious Diseases
JF - Brazilian Journal of Infectious Diseases
IS - 4
ER -