TY - JOUR
T1 - Aetiology, Epidemiology and clinical characteristics of acute moderate-to-severe diarrhoea in children under 5 years of age hospitalized in a referral paediatric hospital in Rabat, Morocco
AU - Benmessaoud, Rachid
AU - Jroundi, Imane
AU - Moraleda, Cinta
AU - Alvarez-Martínez, Miriam J.
AU - Pons, Maria J.
AU - Chaacho, Saad
AU - Hayes, Edward B.
AU - Vila, Jordi
AU - Alonso, Pedro L.
AU - Bassat, Quique
AU - Ruiz, Joaquim
AU - Nezha, Mouane
AU - Tligui, Houssain
AU - Seffar, Myriam
N1 - Publisher Copyright:
© 2015 The Authors.
PY - 2015/1/1
Y1 - 2015/1/1
N2 - The objective of the study was to describe the aetiology, epidemiology and clinical characteristics of the principal causes of acute infectious diarrhoea requiring hospitalization among children under 5 years of age in Rabat, Morocco. A prospective study was conducted from March 2011 to March 2012, designed to describe the main pathogens causing diarrhoea in hospitalized children.2 months and less than 5 years of age. Among the 122 children included in the study, enteroaggregative Escherichia coli (EAEC) and rotavirus were the main aetiological causes of diarrhoea detected. Twelve (9.8%) children were referred to an intensive care unit, while two, presenting infection by EAEC, and EAEC plus Shigella sonnei, developed a haemolytic uraemic syndrome. Additionally, six (4.9%) deaths occurred, with EAEC being isolated in four of these cases. Diarrhoeagenic E. coli and rotavirus play a significant role as the two main causes of severe diarrhoea, while other pathogens, such as norovirus and parasites, seem to have a minimal contribution. Surveillance and prevention programmes to facilitate early recognition and improved management of potentially life-threatening diarrhoea episodes are needed.
AB - The objective of the study was to describe the aetiology, epidemiology and clinical characteristics of the principal causes of acute infectious diarrhoea requiring hospitalization among children under 5 years of age in Rabat, Morocco. A prospective study was conducted from March 2011 to March 2012, designed to describe the main pathogens causing diarrhoea in hospitalized children.2 months and less than 5 years of age. Among the 122 children included in the study, enteroaggregative Escherichia coli (EAEC) and rotavirus were the main aetiological causes of diarrhoea detected. Twelve (9.8%) children were referred to an intensive care unit, while two, presenting infection by EAEC, and EAEC plus Shigella sonnei, developed a haemolytic uraemic syndrome. Additionally, six (4.9%) deaths occurred, with EAEC being isolated in four of these cases. Diarrhoeagenic E. coli and rotavirus play a significant role as the two main causes of severe diarrhoea, while other pathogens, such as norovirus and parasites, seem to have a minimal contribution. Surveillance and prevention programmes to facilitate early recognition and improved management of potentially life-threatening diarrhoea episodes are needed.
UR - http://www.scopus.com/inward/record.url?scp=84919774597&partnerID=8YFLogxK
U2 - 10.1099/jmm.0.079830-0
DO - 10.1099/jmm.0.079830-0
M3 - Artículo
C2 - 25432162
AN - SCOPUS:84919774597
SN - 0022-2615
VL - 64
SP - 84
EP - 92
JO - Journal of Medical Microbiology
JF - Journal of Medical Microbiology
IS - 1
ER -
