TY - JOUR
T1 - A systematic review of population-based studies on lipid profiles in latin america and the caribbean
AU - Carrillo-Larco, Rodrigo M.
AU - Benites-Moya, C. Joel
AU - Anza-Ramirez, Cecilia
AU - Albitres-Flores, Leonardo
AU - Sánchez-Velazco, Diana
AU - Pacheco-Barrios, Niels
AU - Bernabe-Ortiz, Antonio
N1 - Publisher Copyright:
© Carrillo-Larco et al.
PY - 2020/8
Y1 - 2020/8
N2 - We aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Cholesterol [HDL-C; 84 studies; 121,282 people], LDL-Cholesterol [LDL-C; 61 studies; 86,854 people], and triglycerides [TG; 84 studies; 121,009 people]) levels and prevalences were laboratory-based. We used Scopus, LILACS, Embase, Medline and Global Health; studies were from 1964 to 2016. Pooled means and prevalences were estimated for lipid biomarkers from ≥2005. The pooled means (mg/dl) were 193 for TC, 120 for LDL-C, 47 for HDL-C, and 139 for TG; no strong trends. The pooled prevalence estimates were 21% for high TC, 20% for high LDL-C, 48% for low HDL-C, and 21% for high TG; no strong trends. These results may help strengthen programs for dyslipidaemias prevention/management in LAC.
AB - We aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Cholesterol [HDL-C; 84 studies; 121,282 people], LDL-Cholesterol [LDL-C; 61 studies; 86,854 people], and triglycerides [TG; 84 studies; 121,009 people]) levels and prevalences were laboratory-based. We used Scopus, LILACS, Embase, Medline and Global Health; studies were from 1964 to 2016. Pooled means and prevalences were estimated for lipid biomarkers from ≥2005. The pooled means (mg/dl) were 193 for TC, 120 for LDL-C, 47 for HDL-C, and 139 for TG; no strong trends. The pooled prevalence estimates were 21% for high TC, 20% for high LDL-C, 48% for low HDL-C, and 21% for high TG; no strong trends. These results may help strengthen programs for dyslipidaemias prevention/management in LAC.
UR - http://www.scopus.com/inward/record.url?scp=85089634432&partnerID=8YFLogxK
U2 - 10.7554/ELIFE.57980
DO - 10.7554/ELIFE.57980
M3 - Artículo
C2 - 32807300
AN - SCOPUS:85089634432
SN - 2050-084X
VL - 9
SP - 1
EP - 13
JO - eLife
JF - eLife
M1 - e57980
ER -